Gut microbiota alterations and their association with IL6, IL8 and TNFα levels in patients with external genital endometriosis

Today, the association of gut microbiota with external genital endometriosis (EGE) is special scientific interest. The study was aimed to assess alterations taxonomic composition and explore their correlations plasma levels IL6, IL8 TNFα at species level in patients EGE. crosssectional comparative involved 50 EGE (index group) healthy women (control group). changes were assessed. A significant decrease abundance such species, as Coprococcus catu (р = 0.009), Turicibacter sanguinis 0.008) Ruminococcus gnavus < 0.001), along increase Eubacterium ramulus 0.040), Bacterioides dorei Prevotella divia Shigella flexneri 0.001) found Significant between IL6 (r –0.92; р 0.72; 0.77; revealed. findings add available literature data on features some inflammation biomarkers individuals EGE, which can justify further research this area probably open up new approaches treatment disease.